InVivoMAb anti-human CEACAM 1/3/5/6/8
Cat.#
BE0362
规格
1mg
The 6G5j monoclonal antibody reacts with an antigen epitope shared by mouse carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 1, 3, 5, 6, and 8, also known as CD66a, d, e, c, and b. CEACAMs are highly glycosylated membrane proteins belonging to the immunoglobulin superfamily. CEACAMs are involved in cell adhesion, proliferation, differentiation, apoptosis, T and B cell activation and except for CEACAM 8, they also serve as bacterial pathogen receptors. CEACAM 1 is expressed by epithelial, endothelial, and immune cells. CEACAM 3 and 8 are solely expressed in granulocytes, CEACAM 5 in epithelial cells and CEACAM 6 in epithelium and granulocytes. Antibodies against CEACAMs are commonly used in immunohistochemistry and flow cytometry to identify cells expressing the glycoprotein in tissue samples and cell culture. However, CEACAM 1, 5 and 6 are also found in serum where they can be used as tumor markers.
概述
| Isotype | Mouse IgG1, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb mouse IgG1 isotype control, unknown specificity |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Human CEACAM1-Fc fusion protein |
| Reported Applications | Western blot ELISA Immunofluorescence Immunohistochemistry (paraffin) Flow cytometry |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 μM filtered |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_2894780 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
应用
储存
4°C
