InVivoMAb anti-human/ mouse/rat amyloid-beta
Cat.#
BE0368
规格
1mg
The MOAB-2 monoclonal antibody (epitope mapped to residues 1-5 of human Aβ) is a pan-specific antibody. Using synthetic Aβ, it recognizes unaggregated, oligomeric or fibrillar forms of Aβ42 and unaggregated Aβ40, and is selective for human Aβ42 over Aβ40. With synthetic Aβ or human or rodent brain homogenates, MOAB-2 specifically detects Aβ, but not amyloid precursor protein (APP), which is cleaved by β- and Y- secretase to release Aβ. With immunostaining of human or rodent tissue, MOAB-2 detects intraneuronal Aβ, as well as diffuse or compact amyloid plaques.
概述
| Isotype | Mouse IgG2b, λ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb mouse IgG2b isotype control, unknown specificity |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | Human Aβ42 |
| Reported Applications | Western blot Immunohistochemistry Immunofluorescence Immunoprecipitation ELISA |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Purification | Protein A |
| RRID | AB_2927505 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
应用
储存
4°C
