InVivoMAb anti-mouse CD31 (PECAM-1)
Cat.#
BE0377
规格
1mg
The 390 monoclonal antibody reacts with mouse CD31, also known as PECAM-1 (platelet endothelial cell adhesion molecule). CD31 is a 130-140 kDa glycoprotein and member of the immunoglobulin superfamily. CD31 is expressed constitutively on the surface of adult and embryonic endothelial cells and is weakly expressed on platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets. CD31 mediates homophilic and heterophilic cell-cell adhesion and is critical for cell-cell interactions. Ligands for CD31 are reported as CD38 and vitronectin receptor (αvβ3 integrin, CD51/CD61). The 390 antibody has been shown to inhibit in vivo functions mediated by CD31.
概述
| Isotype | Rat IgG2a, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb rat IgG2a isotype control, anti-trinitrophenol |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | C3H/HeJ mouse hematopoietic progenitor cell line 3 |
| Reported Applications | in vivo CD31 blocking Intravital imaging Immunofluorescence Flow cytometry |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Purification | Protein G |
| RRID | AB_2927514 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
应用
储存
4°C
